Rapid molecular assay may help diagnose sepsis

Measuring the levels of RNA biomarkers in blood may help quickly differentiate sepsis from infection-negative systemic inflammation, according to new research. Scientists describe the discovery and validation of a molecular classifier consisting of 4 RNA transcripts (SeptiCyte Lab), which in several selected patient cohorts was able to diagnose sepsis more accurately than procalcitonin or clinical parameters, and more quickly than blood culture.